Skincare with NAD+

NAD+ is a coenzyme that plays a crucial role in cellular energy metabolism and healthy skin function. It's naturally present in all living cells, but production decreases significantly with age - by around 50% by the time you reach 40. This decline is one of the key factors implicated in visible skin aging.

NAD+ (nicotinamide adenine dinucleotide) is a vital coenzyme that plays a central role in skin aging by supporting DNA repair, mitochondrial function (your cells’ battery), controlling inflammation, and the activation of longevity-associated enzymes called sirtuins. 

As we age, NAD+ levels decline due to factors like oxidative stress, chronic inflammation, and a reduced ability to recycle NAD+, leading to impaired skin cell function, reduced collagen production, and increased susceptibility to UV damage. 

This decline contributes to visible signs of aging such as fine lines, loss of elasticity, and dullness. By boosting NAD+ —through topical skincare ingredients like sunflower shoot extract which encourage NAD+ recycling, skin health can be supported by enhancing repair, reducing inflammation, and reinforcing barrier function. This makes it a promising anti-aging strategy, as it helps sustain the fundamental cellular processes that keep skin resilient, youthful, and radiant.

NAD+ is the active, coenzyme form that your body synthesises from vitamin B3. While vitamin B3 (niacinamide) offers its own skin benefits, NAD+ specifically targets cellular energy and anti-aging processes. Think of vitamin B3 as the precursor and NAD+ as the active form your skin cells actually use. At Dr Sam’s, by helping you boost NAD+ with sunflower shoot extract and niacinamide in one routine, you optimise your skin’s ability to stay healthy and resilient. Winning combinations include Flawless Brightly 10% Azelaic Acid Serum and Flawless Moisturiser Intense. 

With consistent use, subtle improvements may be visible within 2-3 weeks, but significant results typically appear after 6-8 weeks of regular application. This timeframe allows for complete skin cell renewal and the full benefits of enhanced cellular energy to become apparent.

This approach is exceptionally well-tolerated (even in sensitive skin) because it's tapping into our skin’s own natural regeneration potential.